Wednesday, February 22, 2012

It is becoming increasingly clear that these ...

anaerobic and aerobic bacteria

Other gram-negative animal and plant pathogens use a novel with an independent protein secretion system as the primary mechanism of virulence. It is becoming increasingly clear that these so-called type III secretion system is introduced (move) proteins in the cytosol of eukaryotic cells where proteins move bacterial pathogenesis facilitate specifically prevents host cell signaling and other cellular processes. Accordingly, some type III secretion system is activated by bacterial contact with the surface of the host cell. Individual type III secretion system to direct secretion and moving different unrelated proteins, which account for the pathogenesis of certain phenotype. In contrast to the secreted virulence factors, most of the 15 to 20 membrane proteins associated type III secretion components of the apparatus are kept between pathogens. Most of the internal components of membrane type III secretion apparatus show additional homology to biosynthetic proteins flagellates, while the conservative outer membrane factor is similar to secretins from type II and other ways of selection. Structurally preserved accompanying that specifically bind to certain proteins secreted play an important role in protein secretion type III, apparently by preventing premature interaction of secreted factors with other proteins. Genes that encode type III secretion systems are grouped, and various evidence suggests that these systems were acquired by horizontal transfer of genetic course of evolution. Expression of type III secretion system coordination is regulated in response to environmental stimuli pass through the network of transcription factors. This review includes a comparison of the structure, function, regulation and impact on host cell type secretion system III in the animal pathogens Yersinia SPP. , Pseudomonas aeruginosa, Shigella Flexner, Salmonella Typhimurium, enteropathogenic E. coli, Chlamydia and SPP. and plant pathogen Pseudomonas syringae, Erwinia SPP order strattera. , Ralstonia solanacearum, Xanthomonas satrezMz and Rhizobium SPP. .

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